Apolipoprotein E (ApoE) is an essential protein for the metabolism of cholesterol and triglycerides.
There are three common genetic variants of the ApoE gene, leading to different performance characteristics of the protein, which in turn is correlated with certain disease susceptibilities. Testing for the genetic variants of the ApoE gene is indicated in those with personal or strong family histories of Alzheimer’s disease, heart disease and stroke. Lifestyle modifications and personalized programs are offered to those with ApoE genotypes associated with increased disease risk.
